AB0215 MAGNITUDE OF THE INFLUENCE BY JOINT INVOLVEMENT ON HEALTH ASSESSMENT QUESTIONNAIRE DISABILITY INDEX SCORE

Background The Health Assessment Questionnaire Disability Index (HAQ-DI) is the best-known index for measuring functional capacity in patients with rheumatoid arthritis (RA). This well known to be influenced by disease activity, aging, joint deformities and pain. However, these parameters are related each other it remains unclear how involvement affects HAQ-DI RA patients. Objectives aim of this study determine using a retrospective cohort study. Methods Patients who have been monitored since first visit tenderness swelling whole body limb joints, patient’s global assessment (PGA), evaluator’s (EGA), pain score visual analog scale (PS), at every were included mean age, HAQ score, PGA, EGA, C-reactive protein (CRP), Sharp/van der Heijde (SHS) collected. Joint Vector (JIV) was used as an lesions. JIV represents prevalence upper X coordinates (Vx), lower Y (Vy), difference between large small joints Z (Vz) [1]. average value triaxial also As preliminary study, correlation all cases collected such patient gender serum albumin level (ALB) evaluated multivariate linear regression analysis. Statistical significance set less than 1.0*10 -10 . Next, association baseline, after 1 year baseline change from year, annual statistically 5.0%. Results A total 601 166 males 435 females data positively correlated male gender, older higher SHS, PS, Vy, Vz beta values 0.09, 0.22, 0.17, 0.19, -0.12, 0.07, 0.11, respectively. CRP, Vy 0.26, 0.13, 0.21, 0.14, 0.10, one SHS PS 0.25, 0.15, Vx, 0.04, 0.67, 0.43, Conclusion These results indicate that there close scores degree pain, deformities, addition, influences scores. In particular, changes governed involvement. effect activity on will largely Reference [1]Nishiyama S, Sawada T, Nishino J, Tohma S. vector: novel measure stratified medicine arthritis. Journal Big Data. 2018;5(1):37. Acknowledgements: NIL. Disclosure Interests None Declared.